HOMA-IR — Insulin Resistance Calculator
Fasting Glucose & Insulin · HOMA-IR & HOMA-B · South Asian Thresholds
Fasting blood values
mg/dL
mmol/L
mU/L (μIU/mL)
pmol/L
ⓘ Critical: Both values must be from the same fasting blood draw — minimum 8 hours fasting, ideally 10–12 hours. Even a small snack invalidates the insulin result. HOMA-IR is only valid in non-diabetic or early diabetic patients not on insulin therapy.
Patient profile
Male
Female
kg/m² — refines risk assessment
Metabolic syndrome markers (optional)
cm — South Asian cutoff: M >90, F >80
mg/dL — elevated in insulin resistance
mg/dL — low HDL is a metabolic syndrome marker
mmHg — hypertension common in IR
Clinical context
Previous result (optional — for trend)
From earlier test — to track improvement
How long ago was previous test
⚠ South Asian threshold: Indian patients are considered insulin resistant at HOMA-IR ≥ 2.5 — lower than the Western cutoff of 3.0. Indians develop metabolic disease at lower BMI and lower insulin levels than Western populations.
Please enter valid fasting glucose and fasting insulin values.
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HOMA-IR
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HOMA-IR classification — South Asian thresholds
HOMA-IR
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HOMA-B (%)
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Fasting glucose
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Fasting insulin
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HOMA-B — Pancreatic Beta Cell Function
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% beta cell function
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Metabolic syndrome assessment
Lifestyle prescription
Intermittent fasting assessment
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Trend analysis
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Clinical flags
ⓘ For clinical decision support only. Not a substitute for physician judgment.
HOMA-IR formula: (Fasting Insulin mU/L × Fasting Glucose mmol/L) ÷ 22.5
(Matthews DR et al., Diabetologia 1985;28:412–419).
HOMA-B formula: (20 × Fasting Insulin mU/L) ÷ (Fasting Glucose mmol/L − 3.5).
South Asian HOMA-IR threshold of 2.5 based on published literature on South Asian metabolic risk
(Deepa M et al., Diabetes Research and Clinical Practice 2006).
HOMA-IR is not valid in patients on insulin therapy, Type 1 diabetes, or with acute illness.