Urine Protein : Creatinine Ratio
UPCR Interpreter · 24-hour protein equivalent · KDIGO 2022
Choose input method
Calculate UPCR
Enter urine protein + creatinine separately
Enter UPCR directly
Ratio already known from lab report
mg/dL (from urine dipstick / lab)
mg/dL (from same urine sample)
Patient context
Male
Female
mg/g — for UPCR vs ACR comparison
For trend analysis
mL/min — contextualises severity
Clinical context
ⓘ UPCR on a random urine sample is a validated surrogate for 24-hour urine protein collection.
A UPCR of 1.0 g/g approximates 1.0 g of protein excreted per day.
Collect a mid-stream urine sample — first morning void is preferred for accuracy.
Please enter valid values to calculate UPCR.
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g/g
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UPCR
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24-hr protein est.
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Category
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Nephrotic range
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Proteinuria severity spectrum
Normal <0.15
Mild 0.15–0.5
Moderate 0.5–1.0
Heavy 1.0–3.5
Nephrotic >3.5
Probable underlying conditions at this UPCR level
Clinical recommendation
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UPCR vs ACR comparison
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Clinical flags
ⓘ For clinical decision support only. Not a substitute for physician judgment.
UPCR interpretation per KDIGO 2022 CKD Guidelines and NICE CKD Guidelines (NG203, 2021).
UPCR correlates with 24-hour urine protein with ±20% variability. Falsely elevated UPCR may occur
with muscle injury, fever, heavy exercise or urinary tract infection. First morning void preferred
for accuracy. Confirm significant proteinuria with repeat testing.